A closer look at the AppliSens Smart pH Sensor.
The AppliSens Smart pH Sensor brings Applikon’s potentiometric measurement expertise to the bioreactor port in a form that prioritises operational consistency over the long haul: a combination glass electrode, an Ag/AgCl/KCl-saturated reference system, an analog mV output via VP8 — and the calibration stability that lets you actually trust the readings two weeks into a perfusion run. Whether you’re holding mammalian cell culture at pH 7.0 ± 0.05, driving a microbial fermentation through an aggressive pH swing, or characterising a new bioprocess on the AppliFlex ST single-use platform, the AppliSens Smart pH delivers ± 0.01 pH accuracy on the Livit Flex platform — the kind of reliability that lets you treat pH as a controlled variable rather than a moving target.
Engineered by Applikon, refined for bioprocessing.
The AppliSens Smart pH Sensor is engineered by Applikon, the worldwide reference in bioprocess instrumentation, with decades of field-proven experience supplying universities, biotech start-ups and biopharmaceutical organisations across the globe. The potentiometric glass-electrode principle is the established standard for bioprocess pH measurement — the AppliSens Smart pH is the modern, drift-optimised expression of that standard, paired with an Ag/AgCl/KCl-saturated reference system and a VP8 connector for direct integration into Livit Flex bioprocess controllers. Resea Biotec is the official Swiss distributor and certified service partner.
Potentiometric measurement and digital signal path.
The AppliSens Smart pH Sensor measures pH using a combination glass electrode: the pH-sensitive glass membrane develops a voltage proportional to the hydrogen-ion activity in the medium, measured against an Ag/AgCl/KCl-saturated reference system. The potentiometric principle generates an analog mV signal across the measurement range of pH 2–9, with ± 0.01 pH accuracy held across the full process window.
Signal delivery runs through the VP8 connector, the industrial standard for bioprocess sensors and the native input on Applikon’s Livit Flex controller. The analog mV signal flows directly into the controller — no signal-conversion modules, no proprietary cabling, no integration unknowns. The same sensor reads identically on every Livit Flex in the lab.
Seven insertion lengths, one sensor family.
The AppliSens smart pH sensor is available in seven insertion lengths to match every Applikon vessel and most third-party bioreactors using PG 13.5 ports. The 12 mm probe diameter is consistent across the range — every length installs through the same standardised port.
110 mm — small benchtop
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1
MiniBio Bioreactor (250 mL – 1 L).
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2
AppliFlex ST 500 mL single-use.
120 mm — short-fill MiniBio and specialised low-volume vessels.
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1
Short-fill MiniBio configurations.
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2
Specialised low-volume vessels.
155 mm — extended-MiniBio and small single-use
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1
MiniBio Plus.
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2
AppliFlex ST 2 L single-use.
235 mm — lab-scale single-use and small Applikon Autoclavable Glass Bioreactor.
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1
AppliFlex ST 3 L single-use.
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2
Small Glass Autoclavable Bioreactor vessels.
325 mm — mid-range Applikon Autoclavable Glass Bioreactor and lab-pilot single-use.
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1
Mid-range Glass Autoclavable Bioreactor vessels.
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2
AppliFlex ST 15 L single-use.
425 mm — bench-scale stainless and larger Applikon Autoclavable Glass Bioreactor.
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1
Applikon BioBench stainless-steel bioreactor.
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2
Larger Glass Autoclavable Bioreactor vessels.
590 mm — pilot-scale stainless.
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1
Applikon BioPilot pilot-scale stainless-steel bioreactor.
The 12 mm probe diameter is consistent across the range — every length installs through the standard PG 13.5 port, with full Applikon controller auto-recognition through the AppliSens driver across the lab-to-pilot vessel range.
