pH Sensors
In the biotech- and pharmaceutical industry it is vital to have precise information about the pH value of the bioprocess. The pH level directly affects viability, productivity, stability of the cells and it influences analysis of active ingredients.
The AppliSens pH+ sensor is specifically designed for long-term, stable and accurate measurements in bioprocesses. The pH+ sensor has a fixed sleeve diaphragm that reduces the influence of the culture medium on the pH measurement.
Compared to classic diaphragm types, the sleeve diaphragm increases measuring accuracy and increases the lifetime of the sensor which is vital for long lasting biotech cultivation processes.
Features
- Robust design by using tempered glass shaft
- Sensor head occupies minimal space on bioreactor top plate
- Accurate measurement
- Low sensitivity to fouling due to sleeve diaphragm
- Stable signal over longer time
- FDA approved materials
- Withstands repeated SIP and CIP cycles
- Standardized PG 13.5 connection guarantees interchangeability with other bioreactor brands
Specifications | |
---|---|
Parameter | As delivered |
pH range | 0 – 12 pH |
Temperature range | 0 – 135°C |
Electrode zero point (E7) | +/-15 mV |
Electrode slope (S4/7) | > 98% |
Isothermal Intersection- pH (Eiso) | 6.5 – 8 |
PH Range | 4 – 9 |
Membrane resistance @ 25°C (ohm) | <1200 |
Membrane resistance @ 37°C (ohm) | <500 |
Calibration drift in Buffer 9 (mV / min) | < 2 |
Stirring Error (Buffer 9 @ 25 °C – pH) | < 0.05 |
Drift 72 hours after Autoclaving pH | < 0.13 |
Zero-point drift per week in PBS (pH) | < 0.05 |
Response Time (pH 9 to 4 @ 25 °C in Seconds) | < 90 |
Response Time 90% (pH 9 to 4 @ 25°C in Seconds) | < 45 |
Response Time (pH 9 to 4 @ 37°C in Seconds) | < 45 |
Response Time 90% (pH 9 to 4 @ 37°C in Seconds) | < 45 |
Facts and Figures
Applications
- Microbial cultures
- Cell cultures
- Batch
- Fed Batch
- Continuous cultures
- Perfusion cultures
Sensor type :
Re-usable pH sensor
Category:
Applications:
Process development, Research Optimization, Pilot Plant, Manufacturing, Fundamental, Screening
Cultivation Volumes:
< 100ml, < 1L, < 10L, < 100L, > 100L
Types:
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