SUB - Control

Controlling Single-use in Pilot & Production

The SUB-Control is a controller designed to work with pilot and production scale single use bioprocessing systems. It can be integrated with the Thermo HyPerforma S.U.B. in the range of 50 to 2000L maximum working volume, or the Thermo HyPerforma S.U.F in 30L of 300L size or Pall or millipore Single use Bioreactors. The SUB-Control is equipped with the latest standard in pump, MFC and sensor technology. The SUB-Control comes in two versions. The SUB-Control ONE is based on the Applikon software platform which has the same advanced features as our bench top scale solutions such as the my-, ez-, ez2- and in-Control. The SUB-Control PLUS is based on PLC technology similar to our i-Control

SUB-Control

Features

  • Options in control platform
    • Applikon proprietary control
    • Siemens PLC
    • Allen Bradley PLC
    • V-Control (Emerson DeltaV)
  • Single-use supplier independent solution based on industry standard hardware
  • Local control and local display
  • Integrates with any factory automation system
  • Fully documented delivery eases validation
  • Can be used in a 21CFR part 11 compliant system
  • As twin or single system availablehjkhkjhj

Specifications

  SUB ONE SUB PLUS
Sensors    
pH Sensor Traditional electrochemical , Single-use sensor options, reduntant options available  
DO Sensor Traditional Polarographic, optical sensor options, Single-use sensor options, redundant options avaliable  
Redox Optional  
Temperature Pt-100, Measurement Range: 0-150 °C accuracy 0,1°C  
Foam/Level Resistive based measurement  
Weight Reactor load cells and balances  
Optional Biomass (Capacitance or optical density), offgas measurements, pressure  
Additional I/O Up to 8 Analog in and 4 Analog out Configurable Up to 8 Digital In and 8 Digital out
Actuators    
Gas Up to 8 MFC’s with solenoid valves or up to 8 rotameters with solenoid valves  
Liquids Up to 4 internal fixed speed pumps, Up to 2 external variable speed pumps Up to 4 internal fixed speed pumps, 2+ external variable speed pumps
Stirring AC or DC motor drive  
Temperature Heating blanket or external Temperature Control Unit (TCU)  
TCU Options Thermoflex Neslab, Lauda, GWK, Polyscience  
Control    
Control Hardware and Software platform Applikon proprietary and Applikon Firmware Siemens, Allen Bradley, iFix, DeltaV
Certifications CE certified, GAMP compliant  
21 CFR part 11 compatible yes  
Communication & SCADA Lucullus PIMS, BioXpert W10, DeltaV, iFix, Applikon OPC server available  
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SUB-Control

Facts and Figures

  • Fully configurable controller based on your requirements
  • Turn-key package with Thermo Fisher HyPerforma S.U.B. and S.U.F.
  • Variety of software platforms available for maximum connectivity.

Applications:

  • Microbial and Cell cultivation
  • Batch, Fed-Batch, Perfusion and Continuous cultivation
  • Single-use bioreactor processes

Dedicated bioreactors:

  • Hyperforma S.U.B
  • Hyperforma S.U.F
  • Pall or millipore Single use Bioreactors

Category:

Applikon Control Systems

Applications:

Process development, Pilot Plant, Manufacturing

Cultivation Volumes:

< 100L, > 100L

Types:

Single-use

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