my-Control bundle

The my-Control bundles are part of Applikons BioBundle range. They are available with 250mL, 500mL, and 1000mL bioreactors for small-scale cultivation. The microbial bundle and the cell culture bundle are ideal setups for your scale-down projects consisting of a MiniBio glass vessel and a my-Control control system.

Features of my-Control bundles

  • Parallel processing system
  • Turnkey bundle solution
  • Modular and configurable bio-reactor system for multiple applications
  • Generate more data in less time
  • Easy setup and operation
  • Cultivate using less medium and less bench space
  • Generate scalable results
my-Control bundle

Specifications of my-Control bundles

Our standard setups are highly sophisticated and can be adapted  based on your application. The cell culture and microbial fermentation bundles share many of its components.  Nevertheless, there are some differences between the bundles which can be further customized to meet your specific needs.

Cell Culture
Microbial
Agitator
Lipseal with marine impeller
Lipseal with Rushton impellers
Exhaust gas
Optional
Gas outlet condenser
pH
Control via liquid alkali pump and CO2 gas supply
Control via liquid alkali and acid addition pump
Temperature
Heating via heating blanket, Peltier optional
Heating and cooling via Peltier system
Dissolved Oxygen
Control via Air and O2 gas supply, Porous sparger
Control via Air supply and agitation speed
Foam
Optional
Control via anti-foam addition pump
 MiniBio 250MiniBio 500MiniBio 1000
Total volume (mL)2905501250
Working volume (mL)2004001000
Minimum working volume (mL)50100200
Aspect ratio total volume2.32.12.3
Aspect ratio working volume1.61.51.9
Dimensions (dxh in mm)180 x 400195 x 400200 x 550
For Autoclaving180 x 250195 x 250200 x 400
 MiniBio 250MiniBio 500MiniBio 1000
Drive systemDirect drive, lipsealedDirect drive, lipsealedDirect drive, lipsealed
Maximum stirrer speed (rpm)50 – 200050 – 200050 – 1750
Maximum impeller tip speed (m/s)2.32.93.5
ImpellersChoice of Rushton and Marine
Gas spargerPorous sparger, open pipe sparger or jet sparger
Gas overlayYes
Exhaust gasElectrically cooled exhaust gas condenser (evaporation <4% per day at 37°C @ 2vvm)
SamplingFixed sample pipe with optional sampling system
DrainingHeight adjustable drain pipe
Additions4 fixed inlet ports and optional micro liquid injectors
Optional inletsSeptum, chemostat tube, liquid entry system
pHMeasurement: 8 mm classic pH sensor
Control: via acid pump (variable speed pump) or CO2 gas in combination with alkali pump (variable speed pump)
DO2Measurement: LumiSens Optical DO2 sensor.
Control: via a combination of N2, Air, O2 (needle valve standard, MFC optional) and agitation
TemperatureMeasurement: Pt-100 sensor in thermowell in topplate
Control: electrical cooling and heating jacket via bioreactor wall
FoamMeasurement: Height adjustable conductivity based foam sensor
Control: anti-foam addition (variable speed pump)
LevelMeasurement: Height adjustable conductivity based level sensor
Control: variable speed pump for liquid addition or removal
Optional sensorsBiomass, Optical Density, O2 and CO2 off gas, weight balance

Lucullus Lite is included with all BioBundles. 

Other software solutions like Standard/Advanced or Expert versions of Lucullus or the BioXpert W10 software can alternatively be supplied with the system. 

my-Control
Facts and Figures

Applications:

  • Screening studies
  • Media optimization
  • Process optimization
  • Cell culture
  • Microbial Fermentation
  • Batch, Fed-Batch, Perfusion and Continuous cultivation

 

Dedicated bioreactors:

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my-Control bundle

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