The Applikon In-Control in detail
The in-Control is Applikon’s compact bioprocess controller for a single laboratory-scale bioreactor — engineered as the direct successor to the ADI 1010 and ADI 1030 platforms that defined the Applikon laboratory installed base for years. With a footprint of 325 × 326 × 188 mm and a weight of just 12 kg, it slots onto the bench where the ADI used to sit and connect to the same vessel without process redesign. Adaptive PID control with autotuning regulates pH (2–14), dissolved oxygen (0–120 %), temperature (+5 to 70 °C), agitation, foam and level; up to four mass-flow controllers or rotameters drive the gas strategy, and up to four variable-speed pumps handle liquid additions. Operators work through an intuitive touchscreen on the unit itself or through any modern web browser — Windows, macOS or Linux on the desktop, iOS or Android on the move.
Experience and quality in every detail.
The defining promise of the in-Control is continuity. If your laboratory currently runs an ADI 1010 or ADI 1030 Bio Controller, the in-Control connects to the same vessel, the same sensors and the same downstream data systems — with no process downtime and no need to re-qualify the bioreactor itself. What changes is the surface: a modern touchscreen, browser-based remote access, adaptive PID with autotuning that compensates as the culture evolves, and a sensor-and-SCADA catalogue that lets the lab finally reach the data depth that ADI-era hardware couldn’t. Every cultivation mode the original controller supported still runs; everything the original controller couldn’t reach (PAT-grade sensor integration, Lucullus PIMS logging, OPC UA hand-off) is now in scope.
Intuitive operation, deep integration
The in-Control is operated through a clean touchscreen on the unit and, when remote work is needed, through any modern web browser — meaning the same controller can be supervised from a PC, an iPad or a phone. Adaptive PID with autotuning means setpoints stay tracked even as broth viscosity, cell density or oxygen demand shift through the run. The controller integrates a wide sensor catalogue including ABER (capacitance), AppliSens, Hamilton ARC DO, BlueSens, Mettler ISM, Densytee, Incyte and Optek, and speaks Lucullus PIMS, OPC UA and V-Control SCADA out of the box — so the in-Control fits cleanly into any existing bioprocess data environment without bespoke integration work.
Compatible Bioreactors and Controllers
The in-Control covers the laboratory-scale segment of the bioreactor stack — single-vessel lab operation across Applikon’s multi-use and single-use ranges, selected third-party platforms, and drop-in replacement for existing ADI 1010 and ADI 1030 installations.
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1
Applikon Glass Bioreactors — multi-use, autoclavable — 2 L – 20 L.
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2
AppliFlex ST — single-use — 500 mL · 3 L · 15 L.
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Millipore Mobius® CellReady — single-use — 3 L.
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Eppendorf BioBlu — single-use — up to 5 L.
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Existing ADI 1010 / ADI 1030 installations — drop-in replacement — as previously installed.
Existing ADI 1010 / ADI 1030 installations transfer to the in-Control as a direct platform-level replacement — no changes to vessel, sensors or piping required, so the upgrade path runs on the same physical hardware your lab is already using.
