Applikon my-Control Bioreactor Controller – 50 mL to 3 L, Compact and Parallel-Capable.

The Applikon My-Control in detail.

The my-Control is Applikon’s most advanced bioreactor controller for small-scale cultivation — built for the screening, media-optimisation and parallel-development work where benchtop space, throughput and consumable cost all matter at once. A single unit runs working volumes from 50 mL through to 3 L total volume on MiniBio vessels (250 / 500 / 1000 mL), Applikon autoclavable glass bioreactors up to 3 L, and small single-use systems including AppliFlex ST, CellReady and Eppendorf BioBlu. The controller stands 19 × 35 cm on the bench, weighs 8.5 kg and ships with a colour-coded indicator band so a row of units stays visually organised across a parallel campaign. Adaptive PID with autotuning regulates pH, dissolved oxygen, temperature, agitation, foam and level; up to four variable-speed pumps and up to four mass-flow controllers handle liquid and gas additions; Peltier elements deliver clean heating and cooling for small vessels, with cold-water-valve cooling available for larger configurations. The killer feature is the Multi-Reactor-Interface: link up to 8 MiniBio reactors to a single console and run a parallel screening campaign that would otherwise consume eight times the bench space and eight times the operator effort.

Experience and quality in every detail.

The my-Control is engineered by Applikon, the worldwide reference in bioprocess instrumentation, with decades of field-proven experience supplying universities, biotech start-ups and biopharmaceutical organisations. Each unit is built to strict industrial standards — full IQ/OQ/PQ support, GAMP 4 compliance, validation documentation and a 21 CFR Part 11-compliant environmental capability. The my-Control is also available as part of the Applikon BioBundles, ready-to-use bioreactor systems that ship pre-configured with a vessel and the matching consumables for immediate start-up. 

Easy operation with professional process control.

The my-Control is operated through its built-in web server — accessible from any computer or tablet on the network, no proprietary software installation required. Adaptive PID with autotuning keeps setpoints tracked even as broth viscosity, cell density or oxygen demand shift through the run. Liquid additions are handled by up to four variable-speed pumps mounted at the front of the unit; gas strategy by up to four mass-flow controllers. Temperature control runs through Peltier elements for small vessels — fast, electrical, no plumbing — and switches to cold-water-valve cooling for larger configurations. A USB connection accepts optional sensors (balances, biomass, fluorophore pH and DO probes), and the controller speaks Lucullus PIMS, OPC UA and V-Control SCADA out of the box for clean integration with any existing bioprocess data environment. Where parallel work is the goal, the Multi-Reactor-Interface stitches up to 8 MiniBio reactors into a single coordinated platform — one operator, one console, eight live runs.

Compatible Bioreactor Systems:

The my-Control covers the small-scale segment of the Applikon range — the volumes where screening, optimisation and early process development happen.

Multi-use bioreactors (autoclavable)

Single-use bioreactors

Process knowledge developed against any my-Control configuration scales cleanly onto the larger Applikon controller range — the same recipe model and parameter set carry from my-Control through to ez2-Control for pilot-scale work and Livit Flex for production.